In materials without spatial inversion symmetry, the spin degeneracy of the conduction electrons can be lifted by an antisymmetric spin–orbit coupling. We discuss the influence of this spin–orbit coupling on the spin susceptibility of such superconductors, with a particular emphasis on the recently discovered heavy Fermion superconductor CePt3Si. We find that, for this compound (with tetragonal crystal symmetry) irrespective of the pairing symmetry, the stable superconducting phases would give a very weak change of the spin susceptibility for fields along the c-axis and an intermediate reduction for fields in the basal plane. We also comment on the consequences for the paramagnetic limiting in this material.